GABAergic System Dysfunction and Challenges in Schizophrenia Research
نویسندگان
چکیده
منابع مشابه
The GABAergic system in schizophrenia.
A defect in neurotransmission involving gamma-amino butyric acid (GABA) in schizophrenia was first proposed in the early 1970s. Since that time, a considerable effort has been made to find such a defect in components of the GABAergic system. After a brief introduction focusing on historical perspectives, this paper reviews post-mortem and other biological studies examining the following compone...
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Many biochemical theories have attempted to explain the pathophysiology of schizophrenia. The dopamine hypothesis is one of oldest and most popular biochemical theories, but it is too simplistic to account for all aspects of the illness. Other neurotransmitter systems, including glutamate, serotonin and -aminobutyric acid (GABA), have been implicated in schizophrenia. The role of the GABA syste...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2021
ISSN: 2296-634X
DOI: 10.3389/fcell.2021.663854